Author/Authors :
Kamino، نويسنده , , Tomoyuki and Murata، نويسنده , , Yoshihisa and Kawai، نويسنده , , Nobuyuki and Hosokawa، نويسنده , , Seijiro and Kobayashi، نويسنده , , Susumu، نويسنده ,
Abstract :
Stereoselective construction of aldol adducts having tertiary alcohol at the α position was achieved via a titanium(IV) enolate derived from a lactate derivative with an Evans chiral auxiliary. The stereochemistry at α-tertiary alcohol could be controlled by selecting the protective group of the starting lactate.