Author/Authors :
Lee، نويسنده , , Hee-Yoon and Tae، نويسنده , , Hyun-Seop and Kim، نويسنده , , Byung Gyu and Choi، نويسنده , , Hyun-Moo، نويسنده ,
Abstract :
The first and practical total synthesis of gelastatins 1, a novel matrix metalloproteinase inhibitor possessing antitumor activity, was accomplished in nine steps starting from Meldrumʹs acid.