Author/Authors :
Danieli، نويسنده , , Bruno and Lesma، نويسنده , , Giordano and Passarella، نويسنده , , Daniele and Piacenti، نويسنده , , Paola and Sacchetti، نويسنده , , Alessandro and Silvani، نويسنده , , Alessandra and Virdis، نويسنده , , Andrea، نويسنده ,
Abstract :
Imino Diels–Alder reactions have been investigated as a new route to sparteine analogues. The first enantioselective synthesis of two diastereoisomeric tricyclic diamines, structurally equivalent to the ABC and BCD rings of the naturally occurring alkaloid, is reported, starting from enantiopure intermediates. The effectiveness of the diamines in the lithiation of N-Boc-pyrrolidine is discussed.
