Pd/P(i-BuNCH2CH2)3N: an efficient catalyst for Suzuki cross-coupling of aryl bromides and chlorides with arylboronic acids

Pd(OAc)2 in combination with the commercially available ligand P(i-BuNCH2CH2)3N catalyzes the Suzuki cross-coupling reaction of a wide variety of aryl bromides and chlorides with arylboronic acids, affording the desired biaryls in excellent yields. It has also been shown that P(NMe2)3 can be employed as a ligand, though with significantly more limited success.