Title of article :
Unexpected synthesis of (trifluoroethyl)pyrimidines from the heterocyclisation of α-trifluoroacetylpropanenitriles
Author/Authors :
Berber، نويسنده , , Hatice and Soufyane، نويسنده , , Mustapha and Santillana-Hayat، نويسنده , , Maud and Mirand، نويسنده , , Catherine، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Pages :
3
From page :
9233
To page :
9235
Abstract :
Some 4-trifluoromethyl-2-aminopyrimidines analogous to trimethoprim and 5-trifluoroethyl-2,4-diaminopyrimidines analogous to pyrimethamine were prepared from enamino(trifluoromethyl)ketones and α-trifluoroacetylpropanenitriles, respectively. A novel heterocyclisation between a trifluoromethylated β-ketonitrile and guanidine was described.
Journal title :
Tetrahedron Letters
Serial Year :
2002
Journal title :
Tetrahedron Letters
Record number :
1659539
Link To Document :
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