Title of article
The synthesis of 2-ketopiperazine acetic acid esters and amides from ethylenediamines with maleates and maleimides
Author/Authors
Abelman، نويسنده , , Matthew M and Fisher، نويسنده , , Karl J and Doerffler، نويسنده , , Edward M and Edwards، نويسنده , , Paul J، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
1823
To page
1826
Abstract
The reaction of substituted ethylenediamines with various fumarates, maleates, and maleimides to form substituted ketopiperazine acetic acid esters and amides was investigated. This method affords a straightforward, high yield approach to a variety of potential peptidomimetics and can yield surprising results with regard to regio- and stereoselectivity.
Keywords
Dimethyl fumarate , ethylenediamine , Dimethyl maleate , ketopiperazine
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1660880
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