Title of article :
Evaluation of Iron Overload in Healthy Adult Residents of Mexico City
Author/Authors :
Baptista-Gonzلlez، نويسنده , , Héctor and Rosenfeld-Mann، نويسنده , , Fanny and Trueba-Gَmez، نويسنده , , Rocيo and Méndez-Sلnchez، نويسنده , , Nahum and Uribe، نويسنده , , Misael، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
Background
cribed the effects of age, gender and body mass index (BMI) on the prevalence of iron overload (IO) in blood donors from Mexico City.
s
s-sectional study of clinically healthy adults was performed. We evaluated serum ferritin (SF) concentration to allow us to establish groups with normal iron stores (SF >30 μg/L) and with IO (SF >200 μg/L and >300 μg/L for women and men), in the following ages groups: 18–29 years, 30–49 years, and 50–64 years, divided by gender.
s
udy included 1757 subjects. Prevalence of IO was 12% in men and 4.8% in women, and prevalence increased in parallel with increasing age (15.6, 25.0 and 29.9% and 3.5, 5.2 and 9.6%, for men and women, respectively). Regression analysis showed that in men there was a significant association of SF and IO with age, BMI and recent blood donation (p <0.01). In women, no differences were seen for BMI and recent blood donation.
sions
highly prevalent in blood donors residing in Mexico City, more so in men than in women. Age, gender and BMI had a positive association with iron stores. This report is the initial contribution towards the study of IO in the Mexican population.
Keywords :
Serum ferritin , Iron Overload , Hemochromatosis , body mass index , Blood donation , Hemoglobin
Journal title :
Archives of Medical Research
Journal title :
Archives of Medical Research