Author/Authors :
Ishida، نويسنده , , Hideyuki and Tatsuta، نويسنده , , Masayuki P. Yamamoto، نويسنده , , Hirofumi and Furukawa، نويسنده , , Hiroshi and Masutani، نويسنده , , Seizou and Takemoto، نويسنده , , Hiroyoshi and Munakata، نويسنده , , Satoru and Miwa، نويسنده , , Hideaki and Sekimoto، نويسنده , , Mitsugu and Monden، نويسنده , , Morito، نويسنده ,
Abstract :
The changes over time in thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD) were studied when colon cancer samples were left at room temperature. The TP levels and the TP/DPD ratio showed no changes over time in either the tumor or normal tissues. DPD levels increased over time in the normal tissues (P=0.015), but showed no changes in the tumor tissues. When the DPD level in normal tissues is to be examined, the samples should be frozen as soon as possible. In all other cases, the ELISA results will not be affected if the samples are frozen within 6 h after collection.
