Title of article :
Protection of poorly nucleophilic pyrroles
Author/Authors :
Handy، نويسنده , , Scott T. and Sabatini، نويسنده , , Jesse J. and Zhang، نويسنده , , Yanan and Vulfova، نويسنده , , Inessa، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
A method for the introduction of carbamate protecting groups on the ring nitrogen of electron-deficient pyrroles has been developed using the commercially available chloroformates and stoichiometric tetrabutylammonium iodide. The method is postulated to generate the more reactive iodoformates in situ to facilitate these protection reactions.
Keywords :
Halogenation , pyrrole , protecting groups , Carbamate
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters