Title of article :
A short and versatile route to chiral spiroketal skeletons
Author/Authors :
Tursun، نويسنده , , Ahmatjan and Canet، نويسنده , , Isabelle and Aboab، نويسنده , , Bettina and Sinibaldi، نويسنده , , Marie-Eve، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
Different chiral spiroketal skeletons are obtained, in a versatile manner, by iterative alkylations of acetone N,N-dimethylhydrazone with iodides 2 followed by a one-pot deprotection/spirocyclization sequence. This methodology has been applied successfully to the synthesis of 1,7-dioxaspiro[5.5]undecane and 1,6-dioxaspiro[4.5]decane systems.
Keywords :
spiroketals , hydrazone , Isopropylidene iodides , stereoselective synthesis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
