Title of article :
Microwave assisted DIC-promoted intramolecular cyclization for solid phase synthesis of trisubstituted imidazolidinones and pyrimidinones
Author/Authors :
Wang، نويسنده , , Xiaobing and Dixon، نويسنده , , Seth and Yao، نويسنده , , Nianhuan and Kurth، نويسنده , , Mark J. and Lam، نويسنده , , Kit S.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Pages :
4
From page :
5747
To page :
5750
Abstract :
A convenient solid phase synthesis of trisubstituted imidazolidinones and pyrimidinones via microwave assisted DIC-promoted intramolecular cyclization is described. Intramolecular cyclization of a resin-bound thiourea prepared by acylation of a dipeptide with an aryl isothiocyanate was rapidly promoted with DIC under microwave to afford imidazolidinones and tetrahydropyrimidinones in good yield and purity.
Keywords :
DIC-promoted , imidazolidinone , Intramolecular cyclization , Pyrimidinone , microwave
Journal title :
Tetrahedron Letters
Serial Year :
2005
Journal title :
Tetrahedron Letters
Record number :
1846476
Link To Document :
بازگشت