Author/Authors :
Kii، نويسنده , , Satoshi and Akao، نويسنده , , Atsushi and Iida، نويسنده , , Takehiko and Mase، نويسنده , , Toshiaki and Yasuda، نويسنده , , Nobuyoshi، نويسنده ,
Abstract :
The organomagnesium complex nBu2iPrMgLi, readily prepared from nBuLi and iPrMgCl (2:1), is quite efficient for the bromine–magnesium exchange of 5-bromo-2-picoline under noncryogenic conditions (at −10 °C). The resulting picolylmagnesium complex reacts with various electrophiles to afford functionalized picolines.
