Investigation of zwitterionic 7-ammonium-7,9-nido-m-carborane

Zwitterionic ammonium-substituted nido m-carborane (7-NH3-7,9-nido-carborane), a novel boron moiety for boron neutron capture therapy, was synthesized and its chemical properties were investigated. This boron cluster system showed unique properties by reacting with carbonyl groups of ketones and aldehydes to generate the corresponding iminium-substituted nido m-carboranes.