Author/Authors :
Hansen، نويسنده , , Jeffrey A. and Smith، نويسنده , , Colin R. and Linder، نويسنده , , Ryan J. and Huffman، نويسنده , , John C.، نويسنده ,
Abstract :
A mixture of cyclohexanone or 4-methylcyclohexanone and an aromatic aldehyde is treated with dimethylsulfoxonium methylide to effect a tandem aldol/epoxidation reaction. The resulting product contains three or four new stereocenters but only one of the possible four or eight diastereomers is formed.
