Author/Authors :
Liu، نويسنده , , Pingli and Huang، نويسنده , , Liang and Lu، نويسنده , , Yuelie and Dilmeghani، نويسنده , , Mina and Baum، نويسنده , , Jean and Xiang، نويسنده , , Tingjian and Adams، نويسنده , , Jeff and Tasker، نويسنده , , Andrew O Larsen، نويسنده , , Rob and Faul، نويسنده , , Margaret M.، نويسنده ,
Abstract :
Synthesis of five and six membered heterocycles, indolines, 2,3-dihydrobenzofurans, chromans, isochromans, 1,2,3,4-tetrahydroquinolines, and 1,2,3,4-tetrahydroisoquinolines, in 70–99% yield by a ligand-free palladium catalyzed reductive Heck cyclization of phenyl bromides and chlorides, under mild conditions, is reported. Water was found to be essential for these reactions.
