Title of article :
Segment coupling to a highly hindered N-terminal, alamethicin-related α-aminoisobutyric acid (Aib) residue
Author/Authors :
Carpino، نويسنده , , Louis A. and Abdel-Maksoud، نويسنده , , Adel Ali and Mansour، نويسنده , , E.M.E. and Zewail، نويسنده , , Mohamed A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Pages :
4
From page :
7404
To page :
7407
Abstract :
A model [6+5] segment coupling process involving a C-terminal valine hexapeptide acid and a resin-attached pentapeptide amide, which N-terminated in a hindered Aib unit, was examined using a variety of HOAt-derived coupling reagents. Best results were observed with N-HAPyU in DCM solvent in which loss of configuration amounted to 5.8%.
Journal title :
Tetrahedron Letters
Serial Year :
2007
Journal title :
Tetrahedron Letters
Record number :
1856857
Link To Document :
بازگشت