Title of article :
Synthesis of (R)-quinuclidine-2-carboxylic acid in enantiomerically pure form
Author/Authors :
Etayo، نويسنده , , Pablo and Badorrey، نويسنده , , Ramَn and Dيaz-de-Villegas، نويسنده , , Marيa D. and Gلlvez، نويسنده , , José A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
Enantiomerically pure (R)-quinuclidine-2-carboxylic acid has been prepared by following two related 7 step synthetic routes in 16% and 19% overall yield, respectively, from a 1,2,4-trisubstituted piperidine that is easily prepared from inexpensive d-mannitol.
Keywords :
piperidines , Intramolecular cyclisations , stereoselective synthesis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
