Author/Authors :
Bernard، نويسنده , , Angela M. and Frongia، نويسنده , , Angelo and Piras، نويسنده , , Pier Paolo and Secci، نويسنده , , Francesco and Spiga، نويسنده , , Marco، نويسنده ,
Abstract :
α-Phenoxy- and phenylthio-ketones have been explored as donors and acceptors in organocatalytic aldol reactions. Our studies have revealed effective methodologies for accessing structurally varied and enantiomerically enriched secondary and tertiary phenylthio- and phenoxy-aldols, expanding the scope and potential synthetic utility of organocatalytic direct aldol reactions.
Keywords :
organocatalyst , Asymmetric reaction , aldol reaction , proline
