Author/Authors :
Yang، نويسنده , , Libin and Yang، نويسنده , , Jing and Li، نويسنده , , Li-Mei and Lei، نويسنده , , Chun and Zhao، نويسنده , , Yong and Huang، نويسنده , , Sheng-Xiong and Xiao، نويسنده , , Wei-Lie and Han، نويسنده , , Quan-Bin and Pu، نويسنده , , Jian-Xin and Sun، نويسنده , , Han-Dong، نويسنده ,
Abstract :
Bisjaponins A (1) and B (2), two new dimeric ent-kaurane diterpenoids connected with a rare four-membered carbon ring, which was formed by [2+2] reaction, were isolated from the aerial parts of Isodon japonicus. Their structures were elucidated by the analysis of spectroscopic evidence including extensive 2D NMR and MS data. Both the compounds were inactive for their cytotoxicity against human tumor cell lines, K562 and HepG2.
Keywords :
Isodon japonicus , Ent-kaurane , Four-membered carbon ring , dimer
