Author/Authors :
Kim، نويسنده , , Mary M. and Ruck، نويسنده , , Rebecca T. and Zhao، نويسنده , , Dalian and Huffman، نويسنده , , Mark A.، نويسنده ,
Abstract :
In this Letter, we describe a practical, green iodination of pyrazoles to form the corresponding 4-iodopyrazole derivatives. The reaction takes place in water, using only 0.5 equiv of iodine and 0.6 equiv of hydrogen peroxide, a system that generates water as the only reaction by-product.