Author/Authors :
Daniels، نويسنده , , R. Nathan and Kim، نويسنده , , Kwangho and Lebois، نويسنده , , Evan P. and Muchalski، نويسنده , , Hubert and Hughes، نويسنده , , Mary and Lindsley، نويسنده , , Craig W.، نويسنده ,
Abstract :
General, high-yielding MAOS protocols for the expedited synthesis of functionalized pyrazolo[1,5-a]pyrimidines and pyrazolo[3,4-b]pyrimidines, as well as their pyrazole precursors, are described amenable to an iterative analogue library synthesis strategy for lead optimization.
