Author/Authors :
Bonache، نويسنده , , M. Angeles and Nuti، نويسنده , , Francesca and Le Chevalier Isaad، نويسنده , , Alexandra and Real-Fernلndez، نويسنده , , Feliciana and Chelli، نويسنده , , Mario and Rovero، نويسنده , , Paolo and Papini، نويسنده , , Anna M.، نويسنده ,
Abstract :
We performed the first synthesis of new Asn derivatives bearing α- or β-ribose as pure anomers, linked by an N-glycosidic bond, on the side chain of the Asn residue orthogonally protected for Fmoc/tBu SPPS, by an efficient five-step strategy with a global yield of 73% starting from d-ribose. These building blocks are obtained in a large scale and can be useful tools for glycopeptide and glycoproteins synthesis.
