Title of article
First total synthesis of (+)-crassalactone A
Author/Authors
Shekhar، نويسنده , , V. and Kumar Reddy، نويسنده , , D. and Suresh Babu، نويسنده , , V. and Chanti Babu، نويسنده , , D. and Venkateswarlu، نويسنده , , Y.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
946
To page
948
Abstract
A simple and highly efficient first total synthesis of cytotoxic (+)-crassalactone A starting from (R)-mandelic acid is described. The strategy involves the osmium tetroxide-catalyzed cis-hydroxylation and the stereoselective addition of ethyl lithiopropiolate to a chiral aldehyde intermediate as key steps.
Keywords
Styrllactones , (+)-Crassalactone A , Lactonization , Goniothalamus , Polyalthia crassa , Cis-hydroxylation
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871069
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