Title of article :
Synthesis and reactivity of non-activated 2-(chloromethyl)aziridines
Author/Authors :
Stankovi?، نويسنده , , Sonja and D’hooghe، نويسنده , , Matthias and Dewulf، نويسنده , , Jo and Bogaert، نويسنده , , Piet and Jolie، نويسنده , , Robrecht and De Kimpe، نويسنده , , Norbert، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Pages :
4
From page :
4529
To page :
4532
Abstract :
An efficient synthesis of non-activated 2-(chloromethyl)aziridines and 2-chloromethyl-2-methylaziridines as new representatives of the class of 2-(halomethyl)aziridines was developed. Furthermore, the reactivity of these azaheterocycles was assessed and compared to that of their brominated counterparts, pointing to a similar profile for 2-(chloromethyl)aziridines and 2-(bromomethyl)aziridines on the one hand, and a different behaviour of 2-chloromethyl-2-methylaziridines versus 2-bromomethyl-2-methylaziridines concerning their aptitude towards ring expansion to azetidines on the other hand.
Keywords :
azetidines , Ring expansion , imines , Selectivity , Aziridines
Journal title :
Tetrahedron Letters
Serial Year :
2011
Journal title :
Tetrahedron Letters
Record number :
1879118
Link To Document :
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