Title of article :
Synthesis of cis,cis-diunsaturated α-meromycolic acid by a palladium-catalysed alkyl–alkyl Negishi reaction
Author/Authors :
Berretta، نويسنده , , Giacomo and Coxon، نويسنده , , Geoffrey D.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
The first total synthesis of cis,cis-diunsaturated α-meromycolic acid has been accomplished using a convergent strategy and a palladium-catalysed alkyl–alkyl Negishi reaction as the key step.
Keywords :
fatty acids , Negishi reaction , Synthesis , Tuberculosis , Drug discovery , Meromycolate , Mycolic acids
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters