Title of article :
Solid-phase based synthesis of biologically promising triazolyl aminoacyl (peptidyl) penicillins
Author/Authors :
Cornier، نويسنده , , Patricia G. and Boggiلn، نويسنده , , Dora B. and Mata، نويسنده , , Ernesto G. and Delpiccolo، نويسنده , , Carina M.L.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
An efficient and versatile methodology for the preparation of valuable triazolyl aminoacyl (peptidyl) penicillins is described. Solid-phase Cu(I)-catalyzed Hüisgen 1,3-dipolar cycloaddition was used as the key step showing general applicability and excellent regioselectivity either with CuI or [Cu(CH3CN)4]PF6 as Cu(I) source.
Keywords :
Peptides , click chemistry , solid-phase synthesis , Penicillins
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
