Title of article
New synthesis of 3,5-disubstituted-5H-thiazolo[3,2-a]pyrimidine via ring annulation of 3,4-dihydropyrimidin-2(1H)-thione using alkynyl(aryl)iodonium salts
Author/Authors
Shelke، نويسنده , , Amol V. and Bhong، نويسنده , , Bhagyashree Y. and Karade، نويسنده , , Nandkishor N.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
600
To page
603
Abstract
A transition metal-free protocol for the synthesis of biologically active thiazolo[3,2-a]pyrimidine derivatives has been achieved by the cyclocondensation of 3,4-dihydropyrimidin-2(1H)-thiones with alkynyl(aryl)iodonium tosylates. This reaction demonstrates another useful application of alkynyl(aryl)iodonium tosylates as synthon of alkynyl cation.
Keywords
cyclocondensation , hypervalent iodine , 2-?]pyrimidine , Biginelli reaction , Alkynyl(aryl)iodonium tosylates
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1883576
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