Title of article :
A simple and expeditious synthesis of 2,3,6-trisubstituted tetrahydropyrans through (3,5)-oxonium-ene cyclization using molecular iodine
Author/Authors :
Prudhvi Raju، نويسنده , , N. and Jagan Mohan Reddy، نويسنده , , B. and Anjibabu، نويسنده , , R. and Muralikrishna، نويسنده , , K. and Subba Reddy، نويسنده , , B.V.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A variety of aldehydes undergo a smooth coupling with 6-methylhept-5-en-2ol in the presence of molecular iodine to afford the 2,3,6-trisubstituted tetrahydropyrans in good yields through 3,5-oxonium-ene cyclization under mild and neutral conditions. This method is simple, convenient, and cost-effective.
Keywords :
3-Isopropenyl-6-methyltetrahydropyrans , Oxonium-ene reaction , Aldehydes , molecular iodine , Alkenols
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
