Title of article :
Direct asymmetric Michael addition of phthalide derivatives to chalcones
Author/Authors :
Luo، نويسنده , , Jie and Jiang، نويسنده , , Chunhui and Wang، نويسنده , , Haifei and Xu، نويسنده , , Li-Wen and Lu، نويسنده , , Yixin، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
The Michael addition of phthalides to chalcones employing a quinidine-derived thiourea catalyst Q-1 has been developed. The reported method led to the synthesis of 3,3-disubstituted phthalide derivatives in excellent yields, with excellent diastereo- and enantioselectivities.
Keywords :
Michael addition , Phthalide derivatives , organocatalysis , Quinine thiourea catalyst , Chalcones
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
