Title of article :
Synthesis, characterization and cytotoxicity of a new palladium(II) complex with a coumarin-derived ligand. Crystal structure of 4-hydroxy-3-(1-(p-tolylimino)ethyl)-2H-chromen-2-one-palladium(II) complex
Author/Authors :
Jevti?، نويسنده , , Verica V. and Pe?i?، نويسنده , , Milica and Radi?، نويسنده , , Gordana P. and Vukovi?، نويسنده , , Nenad and Sukdolak، نويسنده , , Slobodan and Klisuri?، نويسنده , , Olivera and Podolski-Reni?، نويسنده , , Ana and Tani?، نويسنده , , Nikola and Trifunovi?، نويسنده , , Sre?ko R.، نويسنده ,
Abstract :
The new coumarine derivative, 4-hydroxy-3-(1-(p-tolylimino)ethyl)-2H-chromen-2-one, and corresponding palladium(II) complex have been synthesized and characterized by microanalysis, infrared, 1H and 13C NMR spectroscopy. The proposed structure of the complex was confirmed on the basis of an X-ray structural study. In vitro antitumor activity for the ligand and complex was investigated.
Keywords :
Coumarine-derived ligand , Palladium(II) complex , cytotoxicity , crystal structure
