Author/Authors :
Berent، نويسنده , , S and Giordani، نويسنده , , B and Gilman، نويسنده , , S and Trask، نويسنده , , C.L and Little، نويسنده , , R.J.A and Johanns، نويسنده , , J.R and Junck، نويسنده , , L and Kluin، نويسنده , , K.J and Heumann، نويسنده , , M and Koeppe، نويسنده , , R.A، نويسنده ,
Abstract :
Although neuropsychological symptoms are associated with multiple system atrophy (MSA), sporadic olivopontocerebellar atrophy (sOPCA), and dominantly inherited olivopontocerebellar atrophy (dOPCA), the differences between these groups have not been explored. We compared 28 MSA patients on psychiatric rating scales and neuropsychological measures to 67 sOPCA patients, 42 dOPCA patients, and 30 normal controls. Patients with dOPCA, sOPCA, and MSA all exhibited significant deficits on motor-related tasks, as well as relatively mild deficits in cognitive functioning. Patients with MSA had greater neuropsychological dysfunction, particularly in memory and other “higher order” cognitive processes, than patients with either sOPCA or dOPCA.
Keywords :
neuropsychological performance , MSA , sOPCA , dOPCA
