Title of article :
Mathematical modelling of percutaneous absorption
Author/Authors :
Moss، نويسنده , , Gary P. and Wilkinson، نويسنده , , Simon C. and Sun، نويسنده , , Yi، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2012
Abstract :
This review examines recent progress made in the field of modelling and predicting percutaneous absorption. It describes initial qualitative modelling and how quantitative approaches were pioneered and then developed, particularly in the context of the analysis of specific subsets of data. It then focuses on recent developments, including non-linear modelling and discusses recommendations in model construction, development and validation, suggesting that some models do not fit proposed guidelines.
Keywords :
Quantitative structure-/permeability relationships , Machine Learning , Gaussian processes , Transdermal drug delivery , PERCUTANEOUS ABSORPTION
Journal title :
Current Opinion in Colloid and Interface Science
Journal title :
Current Opinion in Colloid and Interface Science