Author/Authors :
Nazari، Fermix نويسنده Students Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran , , Delborde، Yegane نويسنده Students Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran , , Karimitabar، Zahra نويسنده Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, IR Iran , , Ranjbar، Akram نويسنده Department of Toxicology and Pharmacology, Faculty of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran Ranjbar, Akram , Alikhani، Mohammad Yosef نويسنده Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, IR Iran ,
Abstract :
Probiotics are survival microorganisms that, when administered in sufficient amounts, confer health benefits to the host and can be used in an antioxidative role. The antioxidative effect of whole cells and intracellular cell-free extracts of the lactic acid bacteria Lactobacillus acidophilus (PTCC 1643) as a probiotic at three different time intervals was investigated. Antioxidant biomarkers, such as total antioxidant power (TAP), measured with the FRAP (ferric-reducing ability of plasma) method, were evaluated at 24, 48, and 72 hours. The results showed that extracts and bacteria of L. acidophilus were able to significantly increase TAP after 24 and 72 hours. The results showed that the effect of L. acidophilus is time-dependent.
