Title of article :
Atypical Klebsiella Species in a Third Level Hospital as Cause of Neonatal Infection
Author/Authors :
Cifuentes Castaneda Damian David نويسنده Institucion Universitaria Colegio Mayor de Antioquia , Ramirez Duran Ninfa نويسنده Faculty of Medicine, Autonomous University of the State of Mexico , Espinoza Rivera Iliana نويسنده “Monica Pretelini Saenz” Maternal-Perinatal Hospital , Marcela Caro Gonzalez Luz نويسنده “Monica Pretelini Saenz” Maternal-Perinatal Hospital , Pablo Antonio Moreno Perez Martin نويسنده Faculty of Medicine, Autonomous University of the State of Mexico , Mendieta Zeron Hugo نويسنده Faculty of Medicine, Autonomous University of the State of Mexico
Pages :
6
From page :
1
To page :
6
Abstract :
[Background]The opportunistic pathogen Klebsiella pneumoniae is one of the main causes of pediatric bacterial blood stream infections (BSI), which is complicated with sepsis and high mortality.[Objectives]To identify atypical Klebsiella species affecting a sample of infected neonates with low antimicrobial response.[Methods]Multidrug resistant blood cultures for Klebsiella from a Neonatal Service, were submitted to molecular identification by sequencing analysis of 16S ribosomal RNA.[Results]The mean age of the newborns was 14.7 ± 5.6 days. A total of 6 out of 8 cases were sepsis, 1 case of pneumonia, and 1 a catheter-related infection. The molecular identification showed 3 cases of K. pneumoniae subsp. ozaenae, 2 of K. pneumoniae and K. variicola, and 1 case of K. oxytoca. The highest antimicrobial resistance was against cephalosporins and Trimethoprim/sulfamethoxazole.[Conclusions]Klebsiella pneumoniae subsp. ozaenae was responsible for multidrug resistant strains of Klebsiella even in 37.5% of cases. In our clinical setting, the use of Amikacin and carbapenems are still useful to treat neonatal infections by Klebsiella even against K. variicola, which is the most resistant.
Journal title :
Astroparticle Physics
Serial Year :
2018
Record number :
2411553
Link To Document :
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