Author/Authors :
Karimi, Mehran Hematology Research Center - Shiraz University of Medical Sciences, Shiraz , Emad Marvasti, Vahid Hematology Research Center - Shiraz University of Medical Sciences, Shiraz , Rasekhi, Alireza Department of Radiology - Shiraz University of Medical Sciences, Shiraz , Vigayananda Kumar, Perikala Department of Pathology - Shiraz University of Medical Sciences, Shiraz , Bordbar, Mohammadreza Hematology Research Center - Shiraz University of Medical Sciences, Shiraz , Moshiri, Alireza Hematology Research Center - Shiraz University of Medical Sciences, Shiraz , Hasanpour, Peyman Hematology Research Center - Shiraz University of Medical Sciences, Shiraz , Serajzadeh, Kazem Hematology Research Center - Shiraz University of Medical Sciences, Shiraz
Abstract :
β-thalassemia major is a hereditary anemia,
characterized by a genetic deficiency in
the synthesis of the β-globin chain (1). The main
complication of the multiple blood transfusions
to these patients is iron overload and the
deposition of iron in various organs, such as the
reticuloendothelial system, the liver, the heart and
the endocrine glands (2).
