Title of article :
Seroprevalence of hepatitis B virus among hemodialysis patients in Bushehr province, southern Iran
Author/Authors :
Mostaghni, Amir Ahmad Gastroenterohepatology Research Center - Nemazee Hospital - Shiraz University of Medical Sciences, Shiraz , Soltanian, Alireza Department of Internal Medicine - Bushehr University of Medical Sciences, Bushehr , Mokhtari, Elaheh Department of Internal Medicine - Bushehr University of Medical Sciences, Bushehr , Japoni, Sara Gastroenterohepatology Research Center - Nemazee Hospital - Shiraz University of Medical Sciences, Shiraz , Mehrabani, Davood Stem Cell and Transgenic Technology Research Center - Shiraz University of Medical Sciences, Shiraz
Abstract :
Background: Hepatitis B virus (HBV) infection is still reported from adult hemodialysis units.
Objectives: To determine the prevalence of anti-HBs antibody in hemodialysis patients and
the correlation between levels of anti-HBs antibody with other factors.
Patients and Methods: HBsAg, anti-HBs and anti-HBc antibodies level in 119 hemodialysis patients
were evaluated by enzyme-linked immunosorbent assay.
Results: Seroconversion (anti-HBs antibody >10 IU/L) was found in 22 patients. Minimum protective
antibody level was found in patients aged ≥60 years. Statistically significant correlation
was not found between anti-HBs antibody and gender. Ten (8.4%) patients had abnormal
ALT and/or AST. Prevalence of HBsAg, anti-HBc antibody, HBeAg and anti-HBe antibody were
found in 8 (6.72%), 24 (25.16%), 2 (1.68%) and 3 (2.52%) patients, respectively.
Conclusions: Periodic assessment of anti-HBs antibody level is strongly recommended in patients
undergoing hemodialysis.
Keywords :
Hepatitis B virus , Anti-HBs antibody , Hemodialysis , Prevalence , Iran
Journal title :
Astroparticle Physics
