Oseltamivir (Tamiflu)‑induced Bilateral Ciliochoroidal Effusion and Angle Closure Glaucoma: What Type of Idiosyncratic Reaction?

Purpose: To report a case of bilateral acute angle closure glaucoma after one dose of oseltamivir 75 mg. Case Report: A 37‑year‑old man with a history of influenza developed high intraocular pressure and uniformly shallow anterior chamber in both eyes, 5 hours after the first dose of oseltamivir 75 mg. The condition was managed successfully with topical cycloplegic and systemic/topical antiglaucoma medications. Conclusion: Since a presumed idiosyncratic reaction developed right after the first dose of the medication, it challenges the common concept of adaptive immune system involvement in this type of reaction in medication‑related ciliochoroidal effusion.