Title of article :
Magnetic resonance imaging of transplanted stem cell fate in stroke
Author/Authors :
Aghayan, Hamid Reza Tarbiat Modares University , Soleimani, Masoud Tarbiat Modares University , Goodarzi, Parisa Tarbiat Modares University , Norouzi-Javidan, Abbas Tarbiat Modares University , Emami-Razavi, Hasan Tarbiat Modares University , Larijani, Bagher Tarbiat Modares University , Arjmand, Babak Tarbiat Modares University
Abstract :
Nowadays, scientifi c fi ndings in the fi eld of regeneration of nervous system have revealed the possibility of stem cell based therapies
for damaged brain tissue related disorders like stroke. Furthermore, to achieve desirable outcomes from cellular therapies, one needs
to monitor the migration, engraftment, viability, and also functional fate of transplanted stem cells. Magnetic resonance imaging is
an extremely versatile technique for this purpose, which has been broadly used to study stroke and assessment of therapeutic role of
stem cells. In this review we searched in PubMed search engine by using following keywords; “Stem Cells”, “Cell Tracking”, “Stroke”,
“Stem Cell Transplantation”, “Nanoparticles”, and “Magnetic Resonance Imaging” as entry terms and based on the mentioned key
words, the search period was set from 1976 to 2012. Th e main purpose of this article is describing various advantages of molecular
and magnetic resonance imaging of stem cells, with focus on translation of stem cell research to clinical research.
Keywords :
Cell fate , cell tracking , magnetic resonance imaging , nanoparticle , stem cells , stroke , tracking
Journal title :
Astroparticle Physics
