Title of article :
Bowen s Disease Associated With Two Human Papilloma Virus Types
Author/Authors :
Eftekhari ، Hojat - Guilan University of Medical Sciences , Gharaei Nejad ، Kaveh - Guilan University of Medical Sciences , Azimi ، Zeinab - Guilan University of Medical Sciences , Rafiei ، Rana - Guilan University of Medical Sciences , Mesbah ، Alireza Razi Clinico-Pathology Laboratory
Abstract :
Bowen s disease (BD) is an epidermal in-situ squamous cell carcinoma (SCC). Most Human Papilloma Viruses (HPV)-positive lesions in Bowen s disease are localized to the genital region or distal extremities (periungual sites) in which HPV type-16 is frequently detected. Patient was a 64-year-old construction worker for whom we detected 2 erythematous psoriasiform reticular scaly plaques on peri-umbilical and medial knee. Biopsy established the diagnosis of Bowen s disease and polymerase chain reaction assay showed HPV-6, -18 co-infection. Patient was referred for surgical excision.
Keywords :
Bowen s disease , Human papilloma virus , Squamous cell carcinoma
Journal title :
Acta Medica Iranica
Journal title :
Acta Medica Iranica
