Title of article
Microwave-assisted synthesis of 5,10,15,20-tetrakis(4- nitrophenyl)porphyrin and zinc derivative and study of their bacterial photoinactivation
Author/Authors
Rahimi ، Rahmatollah - Iran University of Science and Technology , Fayyaz ، Fatemeh - Iran University of Science and Technology , Rassa ، Mehdi - University of Guilan , Rabbani ، Mahboubeh - Iran University of Science and Technology
Pages
11
From page
175
To page
185
Abstract
In this study, 5,10,15,20-tetrakis(4-nitrophenyl)porphyrin (TNPP) and its zinc porphyrin complex (ZnTNPP) were synthesized in situ using the microwave method and identified by UVVis, FT-IR and 1H NMR. The photostability and photodynamic antimicrobial activity (PACT) of these compounds were investigated on Pseudomonas aeruginosa and Bacillus subtilis under visible light irradiation. MIC, MBC and inhibition zones produced by these compounds were determined and the number of bacteria counted. The results indicated that both compounds have significant stability when illuminated for various illumination periods in nutrient broth media. Both compounds exhibited more effective activity against P. aeruginosa than B. subtilis in nutrient agar.
Keywords
Antimicrobial activity , Bacillus subtilis , Photoinactivation , Pseudomonas aeruginosa , TNPP
Journal title
Iranian Chemical Communication
Serial Year
2016
Journal title
Iranian Chemical Communication
Record number
2461007
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