Rapid Diagnosis of Acute Myocardial Infarction

To improve the specificity of biochemical markers of myocardial infarction (MI) a method to measure cardiac troponin-I (CTn-I) was developed. CTn-I is a protein unique to cardiac muscle and is released after MI. Consecutive 150 patients admitted to the coronary care unit was studied. Value of CTn-I was determined in all samples. CTn-I concentration in the MI patients group was increased compared to that in the control [18.7 +/- 0.13 (mean +/- SD, n = 100) vs. 5.31 +/- 0.13, n = 50] g/l. Measurement of CTn-I accurately detects MI in patients and should facilitate the diagnosis and management of such patients. I