Title of article :
Synthesis of Quinazolinone Derivatives through Multicomponent/Click Reactions
Author/Authors :
Mohammadi Ziarani, Ghodsi Department of Chemistry - Alzahra University , Afsar, Yasaman Department of Chemistry - Alzahra University , Gholamzadeh, Parisa Department of Chemistry - Alzahra University , Badiei, Alireza School of Chemistry - College of Science - University of Tehran
Abstract :
Quinazolinones were synthesized through the one-pot three-component reaction of aromatic aldehydes, isatoic anhydride, and urea under solvent-free conditions using sulfonic acid functionalized mesoporous silica (SBA-Pr-SO3H). The propargyl ether containing 2,3-dihydroquinazolin-4(1H)-ones were reacted with sodium azide in the presence of CuI to gain the new triazole-quinazolinone products.
Keywords :
Dihydroquinazolinone , Quinazolinone , SBA-Pr-SO3H , Click reaction , Isatoic anhydride
