Title of article
Serum Lysophosphatidic Acid Level in Chronic Myeloid Leukemia
Author/Authors
Abouhamzeh ، Beheshteh Department of Anatomy - School of Medicine - AJA University of Medical Sciences , Mirzaii-Dizgah ، Iraj Department of Physiology - School of Medicine - AJA University of Medical Sciences , Ravaei ، Amin Department of Anatomy - School of Medicine - AJA University of Medical Sciences
From page
1
To page
4
Abstract
Background: Chronic myeloid leukemia (CML) is one of the 4 types of leukemia that affects many people each year. This type of leukemia is associated with wide changes in the blood of patients. The aim of this study was to evaluate the serum level of lysophos- phatidic acid (LPA) in patients with chronic myeloid leukemia. Methods: Blood samples were collected from 21 patients with CML and 21 healthy individuals. Serum LPA was measured by the enzyme linked immunosorbent assay (ELISA) method. The data were analyzed by student’s t-test. Results: The results showed that serum LPA level (nmol/mL) of patients (4.5 ± 0.7) was significantly more than the control group (2.2 ± 0.2) (P = 0.004). Conclusions: It seems that serum LPA levels increase in chronic myeloid leukemia, which may be considered as a biomarker in CML.
Keywords
Chronic Myeloid Leukemia , Lysophosphatic Acid , Serum
Journal title
Annals Of Military And Health Sciences Research
Record number
2503513
Link To Document