Title of article :
Synthesis of Some New 4-oxo-4H-Chromene Derivatives Bearing Nitrogen Heterocyclic Systems as Antifungal Agents
Author/Authors :
EL-SAYED ALI, Tarik Ain Shams University, EGYPT , ABDEL-AGHFAAR ABDEL-AZIZ, Salah Ain Shams University, EGYPT , METWALI EL-SHAAER, Hafez Ain Shams University, EGYPT , ISMAIL HANAFY, Faten Ain Shams University, EGYPT , ZAKY EL-FAUOMY, Ali Ain Shams University, EGYPT
Abstract :
Some new 4-oxo-4 H-chromone derivatives bearing nitrogen heterocyclic systems were achieved by treatment of 3-[(4-aminophenylimino)methyIJ-6-chloro-4-oxo-4H-chromene (2) with some aldehydes , cyclic oxygen, and halogen compounds, followed by heterocyclization. Significant antifungal activities were observed for some of the prepared compounds . Structures of all products were confirmed by elemental analysis, IR, lH-NMR, and mass spectra.
Keywords :
Chromone , nitrogen heterocycles , antifungal activity
Journal title :
Turkish Journal of Chemistry
Journal title :
Turkish Journal of Chemistry
