Author/Authors :
SAEED, Aamer Quaid-I-Azam University - Department of Chemistry, Pakistan , RAFIQUE, Hummera Quaid-I-Azam University - Department of Chemistry, Pakistan
Abstract :
A series of novel N-[3-(2-benzo[d]thiazol-2-yl)-4-methylthiazol-2(3H)-ylidene] substituted benzamides (2a--k) were efficiently synthesized by heterocyclization of the corresponding 1-(benzo[d]thiazol-2-yl)-3-aroylthioureas (1a--k). The cyclization was achieved by the reaction of alpha-bromoacteone produced in situ using bromine in dry acetone in the presence of triethylamine.
Keywords :
N , [3 , (2 , Benzothiazolyl) , 4 , methylthiazol , 2(3H) , ylidene] substituted benzamides , 1 , (benzo[d] thiazol , 2 , yl) , 3 , aroylthioureas , 2 , aminobenzothiazoles
