Occurrence of acute monocytic leukemia in a case of untreated Waldenstr?ms macroglobulinemia

Acute myeloid leukemia is a rare complication of untreated Waldenstr?mʹs macroglobulinemia. Although two such cases have been reported, occurrence of acute monocytic leukemia, FAB M5b subtype, in a patient with untreated Waldenstr?mʹs macroglobulinemia has not been reported. The patient had distinct foci with clear demarcation of lymphoid infiltrates and myeloid infiltrates in the bone marrow, representing Waldenstr?mʹs macroglobulinemia and acute monocytic leukemia, indicating the concurrence of two primary malignancies. Am. J. Hematol. 71:94-97, 2002.