Title of article :
A Case of Acute Renal Failure Following Ethylene Glycol Intoxication in a Dog
Author/Authors :
RUSENOV, Anton Trakia University - Faculty of Veterinary Medicine - Department of Internal Diseases, Bulgaria , SIMEONOVA, Galina Trakia University - Faculty of Veterinary Medicine, Bulgaria , SIMEONOV, Radostin Trakia University - Faculty of Veterinary Medicine, Bulgaria , DIMITROV, Rosen Trakia University - Faculty of Veterinary Medicine, Bulgaria , STAMATOVA-YOVCHEVA, Kamelia Trakia University - Faculty of Veterinary Medicine, Bulgaria , NIKOLOV, Yordan Trakia University - Faculty of Veterinary Medicine, Bulgaria , UZUNOVA, Krassimira Trakia University - Faculty of Veterinary Medicine, Bulgaria
From page :
114
To page :
120
Abstract :
The manuscript describes a clinical case of severe oligoanuric acute renal failure in a young dog following ethylene glycol intoxication. Significant deviations were established in urinary renal markers and blood biochemical parameters: severe azotemia, hypocalcaemia, hyperphosphataemia, hyperkalaemia and metabolic acidosis. The ultrasound renal findings demonstrated increased renal cortex echogenicity the typical for ethylene glycol intoxication, with a characteristic halo sign around the medulla. Electrocardiography showed a progressive decrease in amplitudes of P and R peaks, increased sharp edged repolarisation T wave. The performed symptomatic therapy did not lead to favourable outcome due to delayed intervention by the owner and non-administered antidotal therapy. The histopathological finding was consisted in degeneration, necrosis, desquamation of kidney epithelial cells, dilated tubules and multiple calcium oxalate deposits. The described changes, in our opinion, are relevant and could be used for diagnostics of the studied pathology.
Keywords :
Acute renal failure , ethylene glycol , intoxication , glomerular marker , dogs
Journal title :
Journal Of The Faculty Of Veterinary Medicine, Istanbul University
Journal title :
Journal Of The Faculty Of Veterinary Medicine, Istanbul University
Record number :
2597617
Link To Document :
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