Author/Authors :
Ishikawa, Genta Division of Pulmonary Critical Care and Sleep Medicine - Icahn School of Medicine at Mount Sinai, New York, USA , Dua, Sakshi Division of Pulmonary Critical Care and Sleep Medicine - Icahn School of Medicine at Mount Sinai, New York, USA , Mathur, Aditi Division of Pulmonary Critical Care and Sleep Medicine - Icahn School of Medicine at Mount Sinai, New York, USA , Acquah, Samuel O. Division of Pulmonary Critical Care and Sleep Medicine - Icahn School of Medicine at Mount Sinai, New York, USA , Salvatore, Mary Department of Radiology - Columbia University Medical Center, New York, USA , Beasley, Mary B. Department of Pathology - Icahn School of Medicine at Mount Sinai, New York, USA , Padilla, Maria L. Division of Pulmonary Critical Care and Sleep Medicine - Icahn School of Medicine at Mount Sinai, New York, USA
Abstract :
Background. We encounter interstitial lung disease (ILD) patients with psoriasis. (e aim of this case series was to examine clinical
and radiographic characteristics of patients with concomitant psoriasis and ILD. Methods. (is is a retrospective review of our
institutional experience of ILD concomitant with psoriasis, from the database in the Advanced Lung/Interstitial Lung Disease
Program at the Mount Sinai Hospital. Out of 447 ILD patients, we identified 21 (4.7%) with antecedent or concomitant diagnosis
of psoriasis. Clinical, radiographic, pathological, and outcome data were abstracted from our medical records. Results. Median age
was 66 years (range, 46–86) and 14 (66.7%) were male. (irteen (61.9%) had not previously or concomitantly been exposed to
immunosuppressive therapy directed against psoriasis. Two (9.5%) ultimately died. Clinical diagnosis of ILD included idiopathic
pulmonary fibrosis, 11 (52.4%); nonspecific interstitial pneumonia (NSIP), 2 (9.5%); cryptogenic organizing pneumonia, 2 (9.5%);
chronic hypersensitivity pneumonitis, 2 (9.5%); and the others, while radiographic diagnosis included usual interstitial pneumonia pattern, 9 (42.9%); NSIP pattern, 6 (28.6%); organizing pneumonia pattern, 4 (19.0%); hypersensitivity pneumonitis
pattern, 2 (9.5%); and the others. Conclusions. We report 21 ILD cases with antecedent or concomitant diagnosis of psoriasis.
Further prospective studies are required to determine the association between ILD and psoriasis.
