Author/Authors :
Hayashi-Sakai, Sachiko Division of Oral and Maxillofacial Radiology - Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan , Hayashi, Takafumi Division of Oral and Maxillofacial Radiology - Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan , Sakamoto, Makoto Department of Health Sciences - Faculty of Medicine - Niigata University, Niigata, Japan , Sakai, Jun Department of System and Automotive Engineering - Niigata College of Technology, Niigata, Japan , Shimomura-Kuroki, Junko Department of Pediatric Dentistry - School of Life Dentistry at Niigata -The Nippon Dental University, Niigata, Japan , Nishiyama, Hideyoshi Division of Oral and Maxillofacial Radiology - Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan , Katsura, Kouji Division of Oral and Maxillofacial Radiology - Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan , Ike, Makiko Division of Oral and Maxillofacial Radiology - Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan , Nikkuni, Yutaka Division of Oral and Maxillofacial Radiology - Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan , Nakayama, Miwa Division of Oral and Maxillofacial Radiology - Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan , Soga, Marie Division of Oral and Maxillofacial Radiology - Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan , Kobayashi, Taichi Division of Oral and Maxillofacial Radiology - Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Abstract :
Most cases of hypophosphatasia (HPP) exhibit early loss of primary teeth. Results of microcomputed tomography (micro-CT)
analysis of teeth with HPP have rarely been reported. The purpose of the present study was to describe the mineral density
distribution and mapping of exfoliated teeth from an HPP patient using micro-CT. Four exfoliated teeth were obtained from
a patient with HPP. Enamel and dentin mineral densities of exfoliated teeth were measured on micro-CT. The mean values of
enamel and dentin mineral densities in mandibular primary central incisors with HPP were 1.61 and 0.98 g/cm3
, respectively.
The corresponding values in the mandibular primary lateral incisors were 1.60 and 0.98 g/cm3
, respectively. Enamel hypoplasia
was seen in the remaining teeth, both maxillary and mandibular primary canines and first and second molars. Micro-CT enables
nondestructive, noninvasive evaluation and is useful for studying human hard tissues obtained from patients.
