Title of article :
Oral Lichenoid Reaction: An Uncommon Side Effect of Rituximab
Author/Authors :
Giudice, Amerigo Department of Health Sciences - School of Dentistry - Magna Graecia University of Catanzaro, Catanzaro, Italy , Liborio, Francesco Department of Health Sciences - School of Dentistry - Magna Graecia University of Catanzaro, Catanzaro, Italy , Averta, Fiorella Department of Health Sciences - School of Dentistry - Magna Graecia University of Catanzaro, Catanzaro, Italy , Barone, Selene Department of Health Sciences - School of Dentistry - Magna Graecia University of Catanzaro, Catanzaro, Italy , Fortunato, Leonzio Department of Health Sciences - School of Dentistry - Magna Graecia University of Catanzaro, Catanzaro, Italy
Pages :
4
From page :
1
To page :
4
Abstract :
Oral lichenoid reactions (OLR) can be caused by systemic drug exposure. To the best of our knowledge, this is the second report describing a case of OLR induced by rituximab administration in a patient with a diagnosis of non-Hodgkin B-cell lymphoma. After 5 doses of rituximab, a typical pattern of OLP was identified with bilateral and symmetrical lesions on the buccal mucosa and on the right lingual margin. This temporal relationship suggested a probable association between oral lesions and drug therapy. The clinical diagnosis of a rituximab-induced OLR was confirmed by an incisional biopsy reporting a histopathological result of lichenoid mucositis consistent with oral lichen planus. Because of the increasing use of rituximab, it is necessary to know and recognize this uncommon side effect.
Keywords :
Oral Lichenoid Reaction , Uncommon Side Effect , Rituximab
Journal title :
Case Reports in Dentistry
Serial Year :
2019
Full Text URL :
Record number :
2618531
Link To Document :
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